Hallmark has essentially erased my career-threatening joint pain! (Marla A., HALLMARK creator)
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    Scientists Discover the 11 Keys to Healthy Cells

    Nine Powerful Ingredients Work Synergistically to Defend You from

    Age-Related, Environmental, Lifestyle and Genetic Assaults

    HALLMARK™ is the only product that supports all 11 Hallmarks of Health to help:

    •  Quench chronic inflammation*
    •   Promote healthy joint mobility*
    •   Promote DNA Health and Integrity*
    •   Support Healthy Aging Processes*
    •   Support Healthy Cognitive Function* and much more...
    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    You try hard to be healthy. You do your best.

    And though the human body possesses an amazing array of strategies to promote proper cellular function and keep your cells, and thus your body, healthy, it is a losing battle because the world is full of stressors that are hard on your body.

    Environmental factors like chemicals and toxins in our air, water, and food, as well as excessive ultraviolet A&B exposure;

    Lifestyle choices like poor diet, physical inactivity, smoking and excessive alcohol intake; and

    The unavoidable: aging,

    all assault you and your cells every day in ways both noticed and unnoticed, at least initially.

    And that doesn't even consider your genetics, which may be fighting against you as well.

    Detrimental effects accumulate and prevent your body from maintaining the 11 Hallmarks of Healthy Cells. So, what can you do?  

    FIGHT BACK! STOP THE ASSAULT!

    But how?

    You try hard to be healthy. You do your best.

    And though the human body possesses an amazing array of strategies to promote proper cell function to keep you healthy, it's a losing battle because the world is full of stressors that damage your body.

    Environmental factors like chemicals and toxins in our air, water, and food, as well as excessive ultraviolet A&B exposure;

    Lifestyle choices like poor diet, physical inactivity, smoking and excessive alcohol intake; and

    The unavoidable: aging,

    all assault you and your cells every day in ways both noticed and unnoticed, at least initially.

    And that doesn't even consider your genetics, which may be fighting against you as well.

    Damage accumulates and that prevents your body from maintaining the 11 Hallmarks of Health.

    So, what can you do?  

    FIGHT BACK! STOP THE ASSAULT!

    But how?

    HALLMARK is your shield

    Your defense

    Your effortless way to promote all 11 Hallmarks of Healthy Cells 

    While the pharmaceutical industry typically provides bandaid fixes to treat symptoms, nature provides amazingly effective helpers that promote peak cellular health that address root causes. Traditional Chinese and Ayurvedic medicines reflect this fact.

    Healthy cells = Happy you

    Unfortunately, nature's best aides are often found in forms that are not readily consumed or palatable. And even when they are, most are not readily "bioavailable", which means they do not efficiently enter your bloodstream. Instead, they pass right through you without offering the health benefits you are counting on. If nature's helpers are not bioavailable, you are just wasting your money.  

    So, how do you harness the best of nature's genius and promote all 11 Hallmarks of Healthy Cells in your body?  

    Every premium quality ingredient in HALLMARK has been carefully curated by a MD and PhD team based on the most advanced scientific research. Only the most evidence-based and effective of nature's helpers make their way into HALLMARK, including phytonutrients, medicinal mushrooms, adaptogens and supporting ingredients that allow your body to take full advantage of them, working synergistically to keep your cells healthy and you happy.  

    HALLMARK is your path to the 11 Hallmarks of Healthy Cells.

    HALLMARK is your shield

    Your defense

    Your effortless way to promote all 11 Hallmarks of Health 

    While the pharmaceutical industry typically provides bandaid fixes that treat symptoms, nature provides amazingly effective helpers that promote peak cell health that address root causes. Traditional Chinese and Ayurvedic medicines reflect this fact.

    Healthy cells = Happy you

    Unfortunately, nature's best aides are often found in forms that are not readily consumed or palatable. And even when they are, most are not readily "bioavailable", which means they do not efficiently enter your bloodstream. Instead, they pass right through you without offering the health benefits you are counting on. If nature's helpers are not bioavailable, they are not helping you.  

    So, how do you harness the best of nature's genius and promote all 11 Hallmarks of Health in your body?  

    Every premium quality ingredient in HALLMARK has been carefully curated by a MD and PhD team based on the most advanced scientific research. Only the most effective and evidence-based of nature's helpers make their way into HALLMARK, including phytonutrients, medicinal mushrooms, adaptogens and supporting ingredients that allow your body to take full advantage of them, working synergistically to keep your cells healthy and you happy.  

    HALLMARK is your path to the 11 Hallmarks of Health.

    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    But what are the 11 Hallmarks of Health?

    And why do they matter?

    There are 11 primary causes ("hallmarks") of cellular dysfunction. Alone or in combination they can cause cancer and other chronic diseases. HALLMARK is designed to combat all 11, helping your body achieve the normal, healthy state for all 11 hallmarks.  HALLMARK flips the 11 primary causes of cellular dysfunction and disease on their heads and promotes the 11 Hallmarks of Health.  

    Healthy cells function in a predictable way, being "born", living and dying according to highly regulated processes and ordered rules that your cells work hard to maintain. But environmental assaults break down your cells' defenses, disrupt their normal processes and make them break the rules. The result? Cells that misbehave, growing, living and dying when, where and how they should not, and behaving in ways that affect you.

    In a bad way.

    Hallmark 1:  Genetic stability 

    Maintaining the stability of your genome is critical for healthy cellular function - so much so that your cells have multiple mechanisms to maintain the DNA in your genome. But environmental factors, lifestyle choices and aging all fight against your cellular defenses and can harm your genome, changing it from its normal state. This is important because research indicates that genomic instability is a primary factor in cancer, neurodegenerative diseases, immunodeficiency, aging and more [1,44].

    Hallmark 2:  Appropriate response to growth signals

    Growth and maintenance of normal, healthy tissues are highly regulated processes. Normal cells are exquisitely sensitive to growth factors in their local surroundings so that tight control of cell number, tissue architecture and function is maintained. The assaults on your cells by environmental factors, lifestyle choices and aging can cause your cells to alter or lose this sensitivity and thus lose control over normal cell numbers, tissue architecture and function [2].        

    Hallmark 3: Normal response to anti-growth signals

    Growth and maintenance of normal, healthy tissues not only requires growth signals as described for Hallmark 2, but anti-growth signals as well. As expected, normal cells respond to anti-growth signals with a controlled halt of cell division or cell death. Cellular impairment can cause your cells to ignore anti-growth signals so that they grow when and where they should not and lose control over normal cell numbers, tissue architecture and function [3].

    Hallmark 4: Appropriate response to programmed cell death signals

    When the body's repair mechanisms cannot fix affected cells, they are most often eliminated in a highly regulated process called programmed cell death, or apoptosis. Once more, environmental factors, lifestyle choices and aging can cause your cells to ignore their orders, remain well past their welcome and cause havoc [4,5,6].  

    Hallmark 5: Normal response to senescence signals

    Another key mechanism the body uses to prevent affected cells from disrupting normal function is called senescence, in which the cell cycle of a dividing cell is halted [7]. External and internal stressors can cause your cells to ignore senescence signals and cause harm, such as uncontrolled cellular growth, invasiveness and therapeutic resistance [8-10].

    Hallmark 6: Healthy metabolism

    Cellular metabolism is a complex mesh of interconnected reactions, all balanced to maintain your health [11,12]. This balance can be disrupted by cellular damage from environmental factors, lifestyle choices and aging, with wide-ranging, detrimental effects on you [13,40-43].

    Hallmark 7: Healthy inflammatory response

    Healthy inflammation is a short-term defense mechanism used to protect us from infection and injury. However, when our cellular systems sense persistent damage, chronic inflammation can result, which plays a pivotal role in most all chronic diseases and health concerns that afflict Western countries today, including cancer, cardiovascular disease, Alzheimer’s disease, diabetes, Parkinson’s disease and many more [14-18,33-39].

    Hallmark 8: Normal angiogenesis

    Angiogenesis, or the formation of blood vessels, is a critical process in the developing embryo, supplying newly formed tissues the oxygen and nutrients they need to grow. In adulthood, angiogenesis is only activated, briefly and carefully, upon injury or menstruation. However, damage from environmental factors, lifestyle choices and aging can cause your cells to flip the angiogenesis switch back on, feeding those damaged cells all they need to grow [19-22].

    Hallmark 9: Appropriate cellular localization and mobility

    Cells don't live in isolation. Many cell types adhere to each other and to an organized carbohydrate and protein matrix that exists outside the cell, the extracellular matrix. These interactions enable cells to form organized tissues, organ and biological systems. But again, damage from environmental, lifestyle and aging-related sources can alter your cells' ability to connect, letting them invade local tissues and even migrate away from their proper location, often causing you harm [23-25].    

    Hallmark 10: Normal cellular microenvironment

    Cells are in constant communication with other cells in their local microenvironment mostly by sending and receiving chemical signals. This ordered communication is critical for all systemic bodily functions, including immune response, cell growth, differentiation, division and many more. Cellular damage can alter the chemical signals being sent into the local microenvironment, and the results are often detrimental [26-28].  

    Hallmark 11: Normal cellular response to the immune system

    The immune system is our master defender, one with many functions including protecting us from external pathogens like bacteria and viruses and working to kill and recycle damaged cells [29]. However, cellular damage can often accumulate and enable affected cells to evade immune system action [30,31]. These cells are then free to exert their abnormal actions and influences on surrounding cells, harming you.  

    For more information on the science behind the 11 Hallmarks of Health [32], see the citations in the accordion below:

    But what are the 11 Hallmarks of Healthy Cells?

    And why do they matter?

    Healthy cells function in a predictable way, being "born", living and dying according to highly regulated processes and ordered rules that your cells work hard to maintain. But environmental assaults break down your cells' defenses, disrupt their normal processes and make them break the rules. The result? Cells that misbehave, growing, living and dying when, where and how they should not, and behaving in ways that affect you.

    In a bad way.

    Hallmark 1:  Genetic stability 

    Maintaining the stability of your genome is critical for healthy cellular function - so much so that your cells have multiple mechanisms to maintain the DNA in your genome. But environmental factors, lifestyle choices and aging all fight against your cellular defenses and can harm your genome, changing it from its normal state. This is important because research indicates that genomic instability is a primary factor in cancer, neurodegenerative diseases, immunodeficiency, aging and more [1,44].

    Hallmark 2:  Appropriate cellular response to growth signals

    Growth and maintenance of normal, healthy tissues are highly regulated processes. Normal cells are exquisitely sensitive to growth factors in their local surroundings so that tight control of cell number, tissue architecture and function is maintained. The assaults on your cells by environmental factors, lifestyle choices and aging can cause your cells to alter or lose this sensitivity and thus lose control over normal cell numbers, tissue architecture and function [2].        

    Hallmark 3: Normal cellular response to anti-growth signals

    Growth and maintenance of normal, healthy tissues not only requires growth signals as described for Hallmark 2, but anti-growth signals as well. As expected, normals cells respond to anti-growth signals with a controlled halt of cell division or cell death. Cellular impairment can cause your cells to ignore anti-growth signals so that they grow when and where they should not and lose control over normal cell numbers, tissue architecture and function [3].

    Hallmark 4: Appropriate cellular response to programmed cell death

    When the body's repair mechanisms cannot fix affected cells, they are most often eliminated in a highly regulated process called programmed cell death, or apoptosis. Once more, environmental factors, lifestyle choices and aging can cause your cells to ignore their orders, remain well past their welcome and cause havoc [4,5,6].  

    Hallmark 5: Normal cellular response to senescence

    Another key mechanism the body uses to prevent affected cells from disrupting normal function is called senescence, in which the cell cycle of a dividing cell is halted [7]. External and internal stressors can cause your cells to ignore senescence signals and cause harm, such as uncontrolled cellular growth, invasiveness and therapeutic resistance [8-10].

    Hallmark 6: Healthy cellular metabolism

    Cellular metabolism is an astonishingly complex mesh of interconnected reactions, all balanced to maintain your health [11,12]. This balance can be disrupted by cellular damage from environmental factors, lifestyle choices and aging, with wide-ranging, detrimental effects on you [13,40-43].

    Hallmark 7: Healthy inflammatory response

    Healthy inflammation is a short-term defense mechanism used to protect us from infection and injury. However, when our cellular systems sense persistent damage, chronic inflammation can result, which plays a pivotal role in most all chronic diseases and health concerns that afflict Western countries today, including cancer, cardiovascular disease, Alzheimer’s disease, diabetes, Parkinson’s disease and more [14-18,33-39].

    Hallmark 8: Normal angiogenesis

    Angiogenesis, or the formation of blood vessels, is a critical process in the developing embryo, supplying newly formed tissues the oxygen and nutrients they need to grow. In adulthood, angiogenesis is only activated, briefly and carefully, upon injury or menstruation. However, damage from environmental factors, lifestyle choices and aging can cause your cells to flip the angiogenesis switch back on, feeding those damaged cells all they need to grow [19-22].

    Hallmark 9: Appropriate cellular localization and mobility

    Cells don't live in isolation. Many cell types adhere to each other and to an organized carbohydrate and protein matrix that exists outside the cell, the extracellular matrix. These interactions enable cells to form organized tissues, organ and biological systems. But again, damage from environmental, lifestyle and aging-related sources can alter your cells' ability to connect, letting them invade local tissues and even migrate away from their proper location, often causing you harm [23-25].    

    Hallmark 10: Normal cellular microenvironment

    Cells are in constant communication with other cells in their local microenvironment mostly by sending and receiving chemical signals. This ordered communication is critical for all systemic bodily functions, including immune response, cell growth, differentiation, division and many more. Cellular damage can alter the chemical signals being sent into the local microenvironment, and the results are often detrimental [26-28].  

    Hallmark 11: Normal cellular response to the immune system

    The immune system is our master defender, one with many functions including protecting us from external pathogens like bacteria and viruses and working to kill and recycle damaged cells [29]. However, cellular damage can often accumulate and enable affected cells to evade immune system action [30,31]. These cells are then free to exert their abnormal actions and influences on surrounding cells, harming you.  

    For more information on the science behind the 11 Hallmarks of Healthy Cells [32], see the citations in the accordion below:

    Science Behind the 11 Hallmarks

    The importance of supporting the 11 Hallmarks of Health is clear. So how does HALLMARK work to promote the 11 Hallmarks?

    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    HALLMARK is formulated from nine of nature's most potent helpers that promote peak (cellular) health.

    Unlike so many in the industry, the team at NutraFocusMD refuses to play word games when it comes to our ingredients.  HALLMARK contains only the highest quality, highest concentration and most bioactive forms of (always non-GMO) ingredients available and uses no cheap fillers or additives. We use just enough organic rice hulls to enable encapsulation in a vegan-friendly capsule - that's all.

    No Junk = Healthy Cells = Happy You

      We also tell you exactly what is in our products - no hiding behind "proprietary formulas" that leave you wondering what you are actually paying for and consuming. We believe in transparency.

    So, what premium ingredients does HALLMARK contain? And what amazing things can they do for your 11 Hallmarks of Health and beyond?

    HALLMARK includes:

    HALLMARK is formulated from nine of nature's most potent helpers that promote peak cellular health.

    Unlike so many in the industry, the team at NutraFocusMD refuses to play word games when it comes to our ingredients.  HALLMARK contains only the highest quality, highest concentration and most bioactive forms of (always non-GMO) ingredients available and uses no cheap fillers or additives. We use just enough organic rice hulls to enable encapsulation in a vegan-friendly capsule - that's all.

    No Junk = Healthy Cells = Happy You

      We also tell you exactly what is in our products - no hiding behind "proprietary formulas" that leave you wondering what you are actually paying for and consuming. We believe in transparency.

    So, what premium ingredients does HALLMARK contain? And what amazing things can they do for your 11 Hallmarks of Healthy Cells and beyond?

    HALLMARK includes:

    • • Curcumin (≥95% Tetrahydrocurcuminoids)
    • • Green Tea (98/80/60% extract)
    • • Reishi Mushroom (≥30% polysaccharides)
    • • Resveratrol (≥99% trans isomer)
    • • Quercetin (≥98% dihydrate form)
    • • Milk Thistle (≥80% silymarin)
    • • Astragalus membranaceus
    • • Panax notoginseng
    • • Piperine (as BioPerine®)

    CURCUMIN

    Curcumin is the active ingredient in turmeric, famous for its bright yellow-orange color, distinctive flavor and medicinal qualities.  

    Most companies peddle supplements made from powdered turmeric or non-standardized curcumin extracts that pass through you without significant benefit due to low bioavailability and low potency.  

    Even many well-known brands promise to be “pure curcumin” and prominently advertise 95% standardized curcumin, hoping you will think they contain only standardized curcumin – but most are as much as 90% cheap turmeric powder with a dash of standardized curcumin mixed in.  

    We don’t play those games.  

    HALLMARK uses – exclusively – the purest, most potent form of curcumin that exists, patented 95% tetrahydrocurcuminoids (THCs). THCs offer better free radical fighting antioxidant activity [a], better anti-inflammatory activity [b] and are more bioavailable [c] than 95% standardized curcuminoids.  

    Co-formulation with a blend of patented botanical extracts provides a further boost in bioavailability of up to 4000% [d,e], so HALLMARK safely and reliably delivers your benefits.    

    CURCUMIN

    Curcumin is the active ingredient in turmeric, famous for its bright yellow-orange color, distinctive flavor and medicinal qualities.  

    Most companies peddle supplements made from powdered turmeric or non-standardized curcumin extracts that pass through you without significant benefit due to low bioavailability and low potency.  

    Even many well-known brands promise to be “pure curcumin” and prominently advertise 95% standardized curcumin, hoping you will think they contain only standardized curcumin – but most are as much as 90% cheap turmeric powder with a dash of standardized curcumin mixed in.  

    We don’t play those games.  

    HALLMARK uses – exclusively – the purest, most potent form of curcumin that exists, patented 95% tetrahydrocurcuminoids (THCs). THCs offer better free radical fighting antioxidant activity [a], better anti-inflammatory activity [b] and are more bioavailable [c] than 95% standardized curcuminoids.  

    Co-formulation with a blend of patented botanical extracts provides a further boost in bioavailability of up to 4000% [d,e], so HALLMARK safely and reliably delivers your benefits.    

    Curcumin is a powerhouse for Hallmarks:

    Curcumin is a powerhouse for Hallmarks:

    •    2: Promotes appropriate cellular response to growth signals[f]
    •  3: Supports normal cellular response to anti-growth signals[g]
    •  5: Facilitates a normal cellular response to senescence[h]
    •    7: Promotes a healthy inflammatory response[i]
    •  8: Helps maintain normal angiogenesis[j]
    • 10: Encourages a healthy cellular microenvironment[k]
    •    2: Promotes appropriate cellular response to growth signals[f]
    •  3: Supports normal cellular response to anti-growth signals[g]
    •  5: Facilitates a normal cellular response to senescence[h]
    •    7: Promotes a healthy inflammatory response[i]
    •  8: Helps maintain normal angiogenesis[j]
    • 10: Encourages a healthy cellular microenvironment[k]

    Other important benefits of curcumin:

    Other important benefits of curcumin:

    • Promotes healthy cognitive function[l]
    •   Promotes cardiovascular health[m]
    • Supports a healthy mood[n]
    •    Supports healthy aging processes[o,p]
    •  Aids liver health[q]
    •    Helps foster healthy immunity[r]
    •     Promotes healthy joint mobility[s,t]
    •     Works synergistically with trans-Resveratrol[u,v,w]
    •     Works synergistically with Milk Thistle[x]
    •     Works synergistically with Green Tea[y,z,a1]
    •     Works synergistically with Quercetin[b1,c1]
    • Promotes healthy cognitive function[l]
    •   Promotes cardiovascular health[m]
    • Supports a healthy mood[n]
    •    Supports healthy aging processes[o,p]
    •  Aids liver health[q]
    •    Helps foster healthy immunity[r]
    •     Promotes healthy joint mobility[s,t]
    •     Works synergistically with trans-Resveratrol[u,v,w]
    •     Works synergistically with Milk Thistle[x]
    •     Works synergistically with Green Tea[y,z,a1]
    •     Works synergistically with Quercetin[b1,c1]

    For more information on the science behind each ingredient in HALLMARK, see the references in the accordian below the description for Piperine.

    For more information on the science behind each ingredient in HALLMARK, see the references in the accordion below the description for Piperine.

    GREEN TEA

    In Traditional Chinese Medicine (TCM), green tea has been associated with health and longevity for thousands of years [d1]. It has taken Western medicine longer to recognize the power of green tea, but recognize that power it has, with more rigorous academic studies being performed each year than the prior year for nearly twenty consecutive years.      

    Green tea is an abundant sources of free radical fighting, antioxidant polyphenols, but it is the most abundant source of an important sub-class of polyphenols called catechins, and one catechin in particular: epigallocatechin gallate, or EGCG [e1]. The majority of the health benefits attributed to green tea are based on numerous studies conducted on EGCG [f1], which has been shown to effectively scavenge free radicals [g1] and activate your internal free radical fighting mechanisms in numerous ways [h1,i1,j1,k1].

    HALLMARK sources the most potent form of green tea extract available, standardized to 98% polyphenols, 80% catechins and 60% EGCG, bringing you the best of green tea’s benefits.    

    GREEN TEA

    In Traditional Chinese Medicine (TCM), green tea has been associated with health and longevity for thousands of years [d1]. It has taken Western medicine longer to recognize the power of green tea, but recognize that power it has, with more rigorous academic studies being performed each year than the prior year for nearly twenty consecutive years.      

    Green tea is an abundant sources of free radical fighting, antioxidant polyphenols, but it is the most abundant source of an important sub-class of polyphenols called catechins, and one catechin in particular: epigallocatechin gallate, or EGCG [e1]. The majority of the health benefits attributed to green tea are based on numerous studies conducted on EGCG [f1], which has been shown to effectively scavenge free radicals [g1] and activate your internal free radical fighting mechanisms in numerous ways [h1,i1,j1,k1].

    HALLMARK sources the most potent form of green tea extract available, standardized to 98% polyphenols, 80% catechins and 60% EGCG, bringing you the best of green tea’s benefits.    

    Green tea is a powerhouse for Hallmarks:

    •   2: Promotes appropriate cellular response to growth signals[f]
    • 3: Supports normal cellular response to anti-growth signals[g]
    • 4: Appropriate cellular response to programmed cell death[l1]
    • 5: Facilitates a normal cellular response to senescence[h]
    •  7: Promotes a healthy inflammatory response[i]
    • 8: Helps maintain normal angiogenesis[j]
    • 10: Encourages a healthy cellular microenvironment[k]

    Other important benefits of green tea:

    • Promotes healthy cognitive function[m1,n1]
    •   Promotes cardiovascular health[o1,p1,q1]
    •    Supports healthy aging processes[r1,s1,t1]
    •     Helps foster healthy insulin response[u1]
    •    Promotes prostate health[v1]
    •     Promotes healthy joint mobility[w1]
    •     Works synergistically with Curcumin[x1,y1,z1]
    •     Works synergistically with Reishi Mushroom[a2]
    •     Works synergistically with Quercetin[b2]

    REISHI MUSHROOM

    Ganoderma lucidum, a mushroom known as Reishi in Japanese Kampo Medicine and Ling Zhi in TCM, has been a multi-functional staple for over two thousand years. Reishi was considered to be the highest of the "superior plants" in TCM, revered for the wide range of ailments it could treat and its effectiveness.

    Reishi is also considered an adaptogen, which are naturally occurring, non-toxic substances that can help protect your body from stress by stabilizing and optimizing a number of physiological functions. Reishi also exhibits potent free-radical scavenging activity [c2,d2].

    HALLMARK sources the most potent form of Reishi extract available, standardized to ≥30% polysaccharides, bringing you the best of Reishi’s benefits.

    REISHI MUSHROOM

    Ganoderma lucidum, a mushroom known as Reishi in Japanese Kampo Medicine and Ling Zhi in TCM, has been a multi-functional staple for over two thousand years. Reishi was considered to be the highest of the "superior plants" in TCM, revered for the wide range of ailments it could treat and its effectiveness.

    Reishi is also considered an adaptogen, which are naturally occurring, non-toxic substances that can help protect your body from stress by stabilizing and optimizing a number of physiological functions. Reishi also exhibits potent free-radical scavenging activity [c2,d2].

    HALLMARK sources the most potent form of Reishi extract available, standardized to ≥30% polysaccharides, bringing you the best of Reishi’s benefits.

    Reishi is a powerhouse for the following Hallmarks:

    • 3: Supports normal cellular response to anti-growth signals[p6,q6,r6,s6,t6]
    • 4: Appropriate cellular response to programmed cell death[u6,s6,t6]
    • 5: Facilitates a normal cellular response to senescence[v6]
    •  7: Promotes a healthy inflammatory response[w6]
    • 8: Helps maintain normal angiogenesis[x6]
    •  9: Appropriate cellular localization and mobility [e2,f2]
    • 10: Encourages a healthy cellular microenvironment[y6]
    • 11: Promotes normal response to the immune system[g2]

    Other important benefits of Reishi:

    •  Aids liver health[h2,i2]
    •    Helps foster healthy immunity[j2,k2]
    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    trans-RESVERATROL

    As with curcumin, most companies sell supplements made of low concentration "resveratrol" extracts, neglecting to inform potential customers that resveratrol consists of two types of molecules, known as isomers, which are mirror images of each other. Why does that matter?

    The human body is exquisitely tuned to distinguish between isomers, and in the case of resveratrol, the "trans" isomer provides the desired bioactivity, while the "cis" isomer does not. So, companies that sell "50%" or "90%" resveratrol products are actually selling only 25% or 45% active trans-resveratrol. They are taking 100% of your money for 50% bioactivity.  

    Again, we don’t play those games.  

    HALLMARK uses the purest, most potent form of resveratrol available, 99% trans-resveratrol (from Japanese knotweed root), and combines it with other complementary ingredients to synergistically boost its effectiveness.

    trans-RESVERATROL

    As with curcumin, most companies sell supplements made of low concentration "resveratrol" extracts, neglecting to inform potential customers that resveratrol consists of two types of molecules, known as isomers, which are mirror images of each other. Why does that matter?

    The human body is exquisitely tuned to distinguish between isomers, and in the case of resveratrol, the "trans" isomer provides the desired bioactivity, while the "cis" isomer does not. So, companies that sell "50%" or "90%" resveratrol products are actually selling only 25% or 45% active trans-resveratrol. They are taking 100% of your money for 50% bioactivity.  

    Again, we don’t play those games.  

    HALLMARK uses the purest, most potent form of resveratrol available, 99% trans-resveratrol (from Japanese knotweed root), and combines it with other complementary ingredients to synergistically boost its effectiveness.

    trans-Resveratrol is a powerhouse for the following Hallmarks:

    •   1: Genetic stability[l2]
    •   2: Promotes appropriate cellular response to growth signals[f]
    • 3: Supports normal cellular response to anti-growth signals[g]
    • 6: Healthy cellular metabolism[m2]
    •  7: Promotes a healthy inflammatory response[i]
    • 8: Helps maintain normal angiogenesis[j]
    • 10: Encourages a healthy cellular microenvironment[k]

    Other important benefits of trans-Resveratrol:

    • Promotes healthy cognitive function[n2,o2]
    •   Promotes cardiovascular health[p2,q2,r2]
    •    Supports healthy aging processes[s2,t2,u2]
    •    Promotes healthy joint mobility[v2,w2,x2]
    •     Helps foster healthy insulin response[y2,z2,a3]
    •     Works synergistically with Curcumin[u,v,w,b3]
    •     Works synergistically with Green Tea[c3,d3,e3]
    •     Works synergistically with Quercetin[f3,g3,h3,i3]

    QUERCETIN

    Curcumin, resveratrol, green tea, and other potent antioxidants that promote the 11 Hallmarks of Healthy Cells may be better known, but Quercetin deserves its place among the group. Quercetin has been shown to activate the body's antioxidant defense systems [j3,k3,l3] and is a potent anti-inflammatory agent with neuroprotective effects [m3,n3,o3,p3]. It also works with other HALLMARK ingredients synergistically to enhance their collective effect.  

    Once again, HALLMARK uses only the purest, most bioavailable form of quercetin available, 98% quercetin dihydrate (from Japanese pagoda tree flower buds), to maximize benefits for your body and your wallet.

    QUERCETIN

    Curcumin, resveratrol, green tea, and other potent antioxidants that promote the 11 Hallmarks of Health may be better known, but Quercetin deserves its place among the group. Quercetin has been shown to activate the body's antioxidant defense systems [j3,k3,l3] and is a potent anti-inflammatory agent with neuroprotective effects [m3,n3,o3,p3]. It also works with other HALLMARK ingredients synergistically to enhance their collective effect.  

    Once again, HALLMARK uses only the purest, most bioavailable form of quercetin available, 98% quercetin dihydrate (from Japanese pagoda tree flower buds), to maximize benefits for your body and your wallet.

    Quercetin is a powerhouse for the following Hallmarks:

    • 4: Appropriate cellular response to programmed cell death[q3,r3,s3]
    • 5: Facilitates a normal cellular response to senescence[t3,u3,v3]
    •  7: Promotes a healthy inflammatory response[w3]
    • 8: Helps maintain normal angiogenesis[x3,y3,z3,a4]
    •  9: Appropriate cellular localization and mobility [b4,c4,d4]

    Other important benefits of Quercetin:

    • Promotes healthy cognitive function[e4,f4]
    •   Promotes cardiovascular health[g4,h4,i4]
    •    Supports healthy aging processes[j4]
    •     Promotes normal histamine levels[k4,l4]
    •     Works synergistically with trans-Curcumin[b1,c1]
    •     Works synergistically with trans-Resveratrol[f3,g3,h3,i3,m4]
    •     Works synergistically with Green Tea[b2,n4]

    MILK THISTLE (Silymarin)

    Milk thistle, and particularly extracts of milk thistle seeds, have been used in traditional medicine since at least the first century AD. It is known as a formidable warrior against oxidative stress and inflammation [k5,l5,m5,n5,o5], which are the pillars of most chronic ailments [p5,q5,r5,l6,m6].  

    As is our mission, HALLMARK contains the purest, most potent form of milk thistle extract available, standardized to ≥80% silymarin to maximize effectiveness.

    MILK THISTLE (Silymarin)

    Milk thistle, and particularly extracts of milk thistle seeds, have been used in traditional medicine since at least the first century AD. It is known as a formidable warrior against oxidative stress and inflammation [k5,l5,m5,n5,o5], which are the pillars of most chronic ailments [p5,q5,r5,l6,m6].  

    As is our mission, HALLMARK contains the purest, most potent form of milk thistle extract available, standardized to ≥80% silymarin to maximize effectiveness.

    Milk thistle is a powerhouse for the following Hallmarks:

    •   2: Promotes appropriate cellular response to growth signals[z6,a7]
    • 3: Supports normal cellular response to anti-growth signals[b7,c7,d7]
    • 4: Appropriate cellular response to programmed cell death[o4,p4,q4,r4,s4]
    • 5: Facilitates a normal cellular response to senescence[t4,u4,v4]
    • 6: Healthy cellular metabolism[y4,z4]
    •  7: Promotes a healthy inflammatory response[w4]
    • 8: Helps maintain normal angiogenesis[x4,y4,z4]
    •  9: Appropriate cellular localization and mobility [a5,b5,c5]
    • 10: Encourages a healthy cellular microenvironment[e7]
    • 11: Promotes normal response to the immune system[f7]

    Other important benefits of Milk Thistle:

    • Promotes liver health[d5,e5,f5]
    • Promotes healthy cognitive function[g5,h5,i5,j5]
    • Promotes neuroprotective effects[g5,h5,i5,j5]
    •     Works synergistically with curcumin[x]
    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    Astragalus membranaceus and Panax notoginseng

    Astragalus membranaceus root is highly regarded in TCM and considered an adaptogen, working with the body to regulate the effects of physical, mental and emotional stress.  

    Panax notoginseng is also an important TCM herb, notable for the beneficial antioxidant flavonoids found in its root.  

    HALLMARK includes a patented combination of Astragalus and Ginseng called AstraGin®, which has been shown to increase nutrient absorption by up to 92% [e], maximizing the effectiveness of HALLMARK's premium ingredients to promote peak cellular health.

    Astragalus membranaceus and Panax notoginseng

    Astragalus membranaceus root is highly regarded in TCM and considered an adaptogen, working with the body to regulate the effects of physical, mental and emotional stress.  

    Panax notoginseng is also an important TCM herb, notable for the beneficial antioxidant flavonoids found in its root.  

    HALLMARK includes a patented combination of Astragalus and Ginseng called AstraGin®, which has been shown to increase nutrient absorption by up to 92% [e], maximizing the effectiveness of HALLMARK's premium ingredients to promote peak cellular health.

    In addition to increasing the bioavailability of other HALLMARK ingredients, Astragalus and Panax notoginseng are important for the following Hallmarks:

    •   2: Promotes appropriate cellular response to growth signals[s5]
    • 4: Appropriate cellular response to programmed cell death[t5,u5]
    • 5: Facilitates a normal cellular response to senescence[v5]
    •  7: Promotes a healthy inflammatory response[w5,x5,y5,z5,a6]
    • 8: Helps maintain normal angiogenesis[b6]
    • 10: Encourages a healthy cellular microenvironment[n6]
    • 11: Promotes normal response to the immune system[o6]

    Other important benefits of Astragalus and Panax notoginseng:

    •    Supports healthy aging processes[c6,d6,e6,f6,g6]
    • Promotes healthy cognitive function[h6,i6]
    •   Promotes healthy response to stress[j6]
    •   Promotes cardiovascular health[k6]

    Piperine

    Peppercorns are far more than just the most widely used spice in the world. They contain piperine, which possesses powerful antioxidant [g7,h7] and anti-inflammatory activity [h7,i7,j7,k7]. Importantly, piperine is also an effective bioenhancer [l7,m7], which is an agent capable of increasing bioavailability and efficacy of other compound(s) it is administered with, including those in HALLMARK.  

    HALLMARK includes the gold standard ≥95% standardized piperine called BioPerine®, which has been clinically shown to increase curcumin absorption by 2000% [g8], as well as the absorption of numerous other nutrients [h8-j8], again maximizing HALLMARK's ability to promote peak cellular health.

    Piperine

    Peppercorns are far more than just the most widely used spice in the world. They contain piperine, which possesses powerful antioxidant [g7,h7] and anti-inflammatory activity [h7,i7,j7,k7]. Importantly, piperine is also an effective bioenhancer [l7,m7], which is an agent capable of increasing bioavailability and efficacy of other compound(s) it is administered with, including those in HALLMARK.  

    HALLMARK includes the gold standard ≥95% standardized piperine called BioPerine®, which has been clinically shown to increase curcumin absorption by 2000% [g8], as well as the absorption of numerous other nutrients [h8-j8], again maximizing HALLMARK's ability to promote peak cellular health.

    Piperine is a powerhouse for the following Hallmarks:

    •   2: Promotes appropriate cellular response to growth signals[n7,o7]
    • 3: Supports normal cellular response to anti-growth signals[p7]
    • 4: Appropriate cellular response to programmed cell death[n7,p7,q7,r7,s7]
    • 8: Helps maintain normal angiogenesis[t7]
    •  9: Appropriate cellular localization and mobility [n7,o7,u7,v7]
    • 10: Encourages a healthy cellular microenvironment[k]

    Other important benefits of Piperine:

    •   Promotes cardiovascular health[w7,x7,y7]
    • Promotes healthy cognitive function[z7,a8]
    • Supports healthy mood[a8,b8,c8,d8,e8]
    •    Supports healthy aging processes[f8]

    What does this mean for you?

    HALLMARK is the scientifically rigorous, evidence-based supplement that you need to promote all 11 Hallmarks of Healthy Cells and support peak cellular health with potent, free radical fighting antioxidant, anti-inflammatory and adaptogenic ingredients. And again:  

    Healthy Cells = Happy You

    HALLMARK is also GMO free, gluten free, and GMP manufactured in the USA from only the best available ingredients from around the world.

    What does this mean for you?

    HALLMARK is the scientifically rigorous, evidence-based supplement that you need to promote all 11 Hallmarks of Health and support peak cellular health with potent, free radical fighting antioxidant, anti-inflammatory and adaptogenic ingredients. And again:  

    Healthy Cells = Happy You

    HALLMARK is also GMO free, gluten free, and GMP manufactured in the USA from only the best available ingredients from around the world.

    The Science Behind the Benefits

    What do People Say About HALLMARK?

    Here's Jean R. from Illinois:

    "I am a breast cancer survivor having had two surgeries in August 2017. Post surgery and radiation I felt my immune system was drained and my energy depleted. I was having side effects from my aromatase inhibitors that were significantly affecting my day to day living. In discussing these concerns with several doctors I was never given any alternatives or encouragement that things could be different until I talked to Dr. Anderson. She listened to my concerns and asked me thoughtful questions about my lifestyle, including diet, exercise, and supplements. Dr. Anderson explained the science behind HALLMARK and encouraged me to try it.

    I have been using HALLMARK for a little over 6 months. My energy has returned and I feel like my immune system is functioning at an optimal level. The side effects from the aromatase inhibitors are now very minimal and I feel I have my old life back - only better! I have confidence in the ingredients that make up Hallmark as I know they have been thoroughly researched for benefit and purity.

    My husband began taking HALLMARK in December of 2018 and for the first time in many years he made it through the winter season without getting sick. He feels it is making a difference in his health as well.

    If you are on the fence about trying it, I would encourage you to do so ~ there is a 90 day money back guarantee so there is nothing to lose and most importantly - improved health to gain!"

    Here's Dave B. from California:

    "In my hectic life I do not always have the time to exercise and eat the way I’d like to every day. Like most people, I do the best I can, but life can get in the way. I have been taking many supplements (upwards of 8 different supplements a day) to try and make sure that I’m giving my body what it needs to keep my cells healthy. Each morning I look at my pile of vitamins and dread taking them. I’ve been looking for a natural supplement that I can take regularly without having to take many different vitamin/supplements and still feel good about giving my body the nutrients it needs. I now take one supplement in the morning and one with dinner and I feel great both physically and mentally.

    Since taking HALLMARK I have noticed that I’ve been sleeping better, more focused and attack the day with a higher energy level than when I was in my 30’s. I’ve always taken vitamins/supplements but for the first time I’ve found myself making sure I have taken my daily HALLMARK.

    For anyone who is on the fence on whether to try HALLMARK…Jump the fence! HALLMARK has changed the way I approach my day and the energy I have during it. HALLMARK is an easy step to take regarding your health and well-being.

    As well as the benefits you get from taking HALLMARK you also have the peace of mind that you are taking preventative measures to promote a healthier life. I’m glad I found HALLMARK and I wish I had found it sooner!"

    Here's Nadine B. from California:

    "Taking HALLMARK gives me peace-of-mind knowing that I am adding to my body’s defenses against cancer, anti-aging and negative environmental factors.

    Before HALLMARK, I also had a lack of energy and brain fog. But it has improved my energy level and relieved much of my brain fog. Also, on a side note, my fingernails are much stronger than before I started taking the supplement.

    I love how HALLMARK combines into one capsule everything that you need for your cellular health. It’s so handy because then you don’t need to have multiple bottles of supplements.

    I look forward to taking it twice a day. I take it in the morning and in the early evening before dinner; since it gives me an energy boost I don’t want to take it too close to bedtime.

    I eat healthy and exercise, but with all of life’s stresses it gives me a sense of well-being to add as much to my natural defenses as possible, and HALLMARK does that for me.

    You have one body and one life so why not do everything in your power to have the best one available to you?"

    Here's Mari S. from California:

    "NutraFocus gave me my life back. At 57, my hip pain was so bad, I could barely climb a flight of stairs. I was taking 12+ Advil 200mg/day, just to get around. I couldn't go from sitting to standing without pushing up with both arms. I was embarrassed feeling like I was 90. My stepmom suggested I try NutraFocus. That was less than a year ago. I climb 30 flights of stairs/day now, and have maybe had 2 Advil in the last 6 months, and that was for a headache! I will never go without it!"

    Here's Joan W. from California:

    "I know it is helping my over all health and well being plus, the anti-inflammatory effect is noticeable. As one with significant osteoarthritis, ANY reduction in pain is beneficial."

    Those Results Speak for Themselves!

    Trying HALLMARK is Risk-Free!

    Your satisfaction is our #1 priority at NutraFocusMD, so we are proud to offer a Total Satisfaction Guarantee

    If you are unhappy with a product, simply return it within 90 days of placing your order and we'll give you a full refund

    It's just that simple.

    So what are you waiting for?

    There is nothing stopping you from supercharging your cellular health!

    Trying HALLMARK is Risk-Free!

    Your satisfaction is our #1 priority at NutraFocusMD, so we are proud to offer a Total Satisfaction Guarantee

    If you are unhappy with a product, simply return it within 90 days of placing your order and we'll give you a full refund

    It's just that simple.

    So what are you waiting for?

    There is nothing stopping you from supercharging your cellular health!

    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    Why NutraFocusMD?

    Our Mission

    It's simple - we want to help you achieve your optimal health.

    With optimal health, we can maximize our potential, which benefits ourselves, our families, our communities and our world.

    More about Our Mission

    Our Values

    We are guided by five core principles: Honesty, Passion, Independence, Curiosity and a little bit of Rebellion.

    An odd mix, perhaps, but it works for us, and we think our results will work for you!

    More about Our Values

    Our Promise

    We promise to deliver Superior Quality, Superior Science, Superior Efficacy and Superior Safety, all with no risk to you!

    • Healthy Cells = Happy You.

    It's more than a slogan, it is what's waiting for you.

    Meet the Docs

    Marla Anderson, MD, FACS, is a practicing surgeon with a focus on treating patients with breast cancer. She received her MD from Northwestern University and B.S. in Biochemistry from the University of California, Davis. Continual learning feeds her, and her major areas of interest are mindfulness, optimal health, the science of the body and integrative and functional medicine. Her passion is to create products that positively affect people so they can live their best life. Home is where the heart is, and Marla's heart is with God, her husband and her three children.

    Jeff Anderson, PhD, is a biochemist who has a passion for discovering what makes the body and mind perform at their peak. "Biochemistry is the root to understanding why the body and mind are performing as they are -- sub-optimally, optimally and even super-optimally -- and also the key to understanding what can be done to help climb that ladder of performance so that we can all feel and perform at our best. We at NutraFocusMD use those principles in creating our products."  

    While Jeff has spent much of his career in the pharmaceutical and biotechnology industries, he was fortunate to work with companies that were innovative, resisting the all-too-common band-aid model of the pharma world. Nevertheless, he knew there were safer and more effective ways to address many health problems and promote optimal, heathy function, and he is excited to devote his passion, time and energy into delivering those results for you.

    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!
    • Promotes the 11 Hallmarks of Health*  
    • Supports healthy aging processes*    
    • Promotes healthy cognitive function*    
    • Promotes cardiovascular health*    
    • Promotes healthy joint mobility*    
    • Helps foster healthy immunity*      
    • Promotes liver health, and more*    

    Suggested Use: For long-term maintenance of your 11 Hallmarks of Healthy cells, take 1 capsule, twice daily or 2 capsules once daily. For active support of your Hallmarks, take 2 capsules, twice daily, or as recommended by your healthcare practitioner.

    Additional Tips: Take HALLMARK consistently. Eat antioxidant-rich foods (e.g., vegetables, seeds, nuts, dark berries) and avoid highly processed foods and refined sugars.

    Suggested Use: For long-term maintenance of your 11 Hallmarks of Health, take 1 capsule, twice daily or 2 capsules once daily. For active support of your Hallmarks, take 2 capsules, twice daily, or as recommended by your healthcare practitioner.

    Additional Tips: Take HALLMARK consistently. Eat antioxidant-rich foods (e.g., vegetables, seeds, nuts, dark berries) and avoid highly processed foods and refined sugars.

    Selected FAQs

    Who can benefit from HALLMARK?

    HALLMARK is for anyone who wants to promote their peak cellular health! After all, Healthy Cells = Happy You.  

    Whether you are worried about specific health problems and effects from environmental factors, lifestyle choices, aging and your genetics, or, even though you feel good, you worry about the potential risks from the same, your cells can benefit from HALLMARK.

    What does "active support" and "long term maintenance" mean?

    For MAINTENANCE of your 11 Hallmarks of Health, the suggested dose is 2 capsules once a day (upon rising) or 1 capsule twice per day (upon rising and at bedtime). Because HALLMARK is more potent and absorbable than most supplements of its type (though no others promote all 11 Hallmarks!), 2 capsules once per day works fine - but 1 capsule twice per day is even better. You can safely double the dose for ACTIVE SUPPORT of your 11 Hallmarks (2 capsules, twice per day) to help promote the 11 Hallmarks against acute effects from environmental factors, lifestyle choices, aging and your genetics.    

    Because each individual is different, we recommend consulting with your healthcare provider before taking any supplement.

    Is there scientific research behind HALLMARK?

    Absolutely! The positive, health-promoting effects of the ingredients in HALLMARK and the science behind the 11 Hallmarks of Health are supported by thousands of peer-reviewed, scientific articles, over 260 of which are cited above and listed in the two accordians (labeled "The Science Behind the 11 Hallmarks" and "The Science Behind the Benefits").

    Is HALLMARK allergen free?

    Yes, HALLMARK is allergen free, as well as 100% vegetarian, gluten free, GMO free and contains no artificial flavors, preservatives, fillers or colors. HALLMARK contains only the highest quality, highest concentration and most bioactive forms of ingredients available. We use just enough organic rice hulls to enable encapsulation in a vegan-friendly capsule - that's all.

    Are there any contraindications or cautions for HALLMARK?

    HALLMARK has no known adverse effects or contraindications under the suggested use conditions (see "active support" and "long term maintenance" FAQ above.

    It is always advisable to consult your health care practitioner about the use of any dietary supplement that contains herbs. If you are nursing, pregnant or considering pregnancy, you should always, without exception consult your healthcare practitioner prior to use.

    Where are your ingredients sourced?

    A common question we receive is what is the original source of the various ingredients that go into our supplements. It’s a good question, and one that exposes another important question. As for the sources of various ingredients, it depends where the best ingredients come from! If the USA, then we buy ingredients originating from there. If China or India is the premier source for an ingredient, we buy from China or India from highly reputable suppliers. In other words, we source our materials from all over the world based on who offers the best quality, potency and bioactivity, and if it does not meet NutraFocusMD's exacting standards, it never reaches you!

    The deeper question is that of purity and cleanliness. Our products are all manufactured in GMP (Good Manufacturing Practice) certified facilities, using the highest quality standards. All products undergo testing to confirm ingredients and label claims, as well as heavy metal and microbial analyses (including but are not limited to: mercury, cadmium, lead, yeasts, molds, salmonella, E. coli, other coliforms and staphylococcus aureus).

    Can I take HALLMARK with my existing supplements?

    It is always the best practice to talk with a doctor or pharmacist well versed in nutrition about any supplement or vitamin you want to take prior to taking it, just to make sure they won’t interfere with any other medication you may be taking.  

    HALLMARK has no known adverse effects or contraindications under the suggested use conditions (see "active support and long term maintenance" FAQ).

    If you are nursing, pregnant or considering pregnancy, you should always, without exception consult your healthcare practitioner prior to use of any new vitamin or supplement.

    More Questions? See the full FAQ.

    I WANT HEALTHY CELLS!
    I WANT HEALTHY CELLS!

    *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.